We've updated our privacy policy. Tumor-suppressor genes, function like brakes, 1. the process of custom brokerage. A normal physiological response to specific, Internucleosomal cleavage leads to laddering of, Cytoplasma shrinks without membrane rupture. 1007 0 obj << /Linearized 1 /O 1019 /H [ 2185 835 ] /L 737686 /E 118776 /N 26 /T 717426 >> endobj xref 1007 34 0000000016 00000 n Enjoy access to millions of ebooks, audiobooks, magazines, and more from Scribd. different processes Apoptosis and necrosis have different Then you can share it with your target audience as well as PowerShow.coms millions of monthly visitors. Individual cells fragment and are consumed by phagocytes to give the appearance of clear spaces filled with cellular debris. Our product offerings include millions of PowerPoint templates, diagrams, animated 3D characters and more. Hb```f`d`@(!(! !Nly,d7ZLh9l "p9:)o-*v`cVu5Y - 5sMS4,JG!96Z@! Learn faster and smarter from top experts, Download to take your learnings offline and on the go. Recently defined genetic connections between C. elegans cell death and mammalian apoptosis have emphasised the value of this system as a model for cell death in mammalian cells, which, inevitably, is more complex. ladderingof DNA, DNA cleaved into non-random fragments 180-200 bp fragments patern) Prelytic DNA fragmentation Release of various factors into 0000049844 00000 n Significant inflammatory response Affects individual cells Induced gb@ !&NGWa``dl5XT *I:*stzRdN2UOo&I.3Q'3/&N9buJ(rNEn1`s:Aa6q Al% 0000091933 00000 n electrophoresis) Postlytic DNA fragmentation (= late event of Often found during tissue homeostasis, embryogenesis, immunological reactions and development of nervous systems. Just like the old leaves 'falloff' from the trees without affecting the life of the plant, the apoptotic cell death will not interfere with the functioning of the organ and organism. After an appropriate stimulus, the first stage of apoptosis or "decision phase" is the genetic control point of cell . 0000006098 00000 n 0000047427 00000 n 2H6 The signals inducing apoptosis are very varied and the same signals can induce differentiation and proliferation in other situations. hormonal environment) Phagocytosis by adjacent cells or macrophages 11.20 (dr. yasmeen hashim) apoptosis (mechanism in normal tissues. repair without eliciting a severe host reaction, thus keeping the Recognition, Mechanisms of Apoptosis The fundamental events in apoptosis is Synthesized as inactive zymogens (PROCASPASES), Digestion of DNA starts after 2 hrs 3&4 hrs after If you need only one SlideShare download then you do not need to download all SlideShare, with our tool you can download one SlideShare in different formats. An understanding of the underlying mechanism of apoptosis is important as it plays a pivotal role in the pathogenesis of many diseases. startxref The PowerPoint PPT presentation: "Apoptosis (Programmed Cell Death)" is the property of its rightful owner. hypoxia, ischemia, metabolic poisons) Phagocytosis by macrophages G`Gcw*m=z??_SA:BqVX[5MG_6wY ' @`upJ'8i&. atrophy in parenchymal organs after duct obstruction Apoptosis Programmed cell death NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE Page 5 "Death Becomes Us" by Michele M. Cox "Ok, so the initiator caspase is triggered by a signal outside the cell, but what signals would the cell receive that will cause it or want it to kill itself?" Derek thought. Viral infection can induce apoptosis and occurs when one or several cells of a living . Apoptosis A pathological response to injury Chromatin clumping Mitochondria swelling and rupture Plasma membrane lyses Cell contents spill out A normal physiological response to specific suicide signals Chromatin condenses Internucleosomal cleavage leads to laddering of DNA Cytoplasma shrinks without membrane rupture In adults, apoptosis is used to rid the body of cells that have been damaged beyond repair. d1AdW$PK-}$q$xs6W=F0i/8ZU u%IssC0st^_o ~qBA@FS/9!B5 6mqR!I7"4B of apoptosis. 0000001034 00000 n 1. 0000004285 00000 n Algunas de ellas (bc1-2 y bc1-XL) son anti apoptticas mientras que otras (Bad y Bax) son pro apoptticas. Apoptosis - Programmed Cell Death (True/False) In adult tissues cell death exactly balances cell division In apoptosis the cell destroys itself from within and avoids leakage of the cell contents into the extracellular space. @D6!;5%\Dgh39RG06Wd=Tnb=&g!^;\. %PDF-1.4 % Breakdown Phosphatidylserine Thrombospondin Phagocytic (Apoptosis) We've encountered a problem, please try again. 0000002019 00000 n If so, just upload it to PowerShow.com. viral proteins Mitochondrial pathway, The death receptor pathway Extrinsic pathway, Antiapoptotic Proapoptotic Bcl-2 family members A very large The apoptotic cells are enlarged, pink from loss of cytoplasmic detail, and without nuclei. Weve updated our privacy policy so that we are compliant with changing global privacy regulations and to provide you with insight into the limited ways in which we use your data. pathologic situations, APOPTOSIS Apoptosis in physiologic situations Vaux and 39 In cancer cells . death for removal of unwanted individual cells, Cells die by one of two mechanisms Two physiologically Apoptosis is a biological process which occurs in all multicellular organisms including plants and animals. 0000005463 00000 n You might even have a presentation youd like to share with others. And, again, its all free. Instant access to millions of ebooks, audiobooks, magazines, podcasts and more. programmed Apoptosis / dental crown & bridge courses, Apoptosis and the response to chemotherapy. ?i"$"b(#|cEQFFWWj-Fu,EKs>4sPqpQ kX Apoptosis is a programmed cell death to ensure the maintenance of tissue homeostasis in an organism by getting rid of damaged cells that might interfere with normal functions. a la apoptosis. When a cell undergoes apoptosis, the entire cell, including the nucleus, separates into numerous fragments (i.e., apoptotic bodies). 0000049636 00000 n oligonucleosomes By Ca2+-and Mg2+-dependent endonucleases DNA In this example, hepatocytes are dying individually (arrows) from injury through infection by viral hepatitis. 0000004492 00000 n Programmed cell death during adult stage. 0000001400 00000 n Why do you think that this occurs via a different mechanism than in necrosis? 0000008842 00000 n characteristics. Looks like youve clipped this slide to already. Apoptosis can be triggered by various stimuli from outside or inside the cell, e.g. by physiological stimuli (lack of growth factors, changes in 0000003839 00000 n If so, share your PPT presentation slides online with PowerShow.com. Well convert it to an HTML5 slideshow that includes all the media types youve already added: audio, video, music, pictures, animations and transition effects. 0000017065 00000 n 0000008818 00000 n 0000000016 00000 n 46 0 obj<> endobj 0000003600 00000 n cell into smaller bodies Mitochondria become leaky due to pore PowerShow.com is brought to you byCrystalGraphics, the award-winning developer and market-leading publisher of rich-media enhancement products for presentations. These include: oxidants, bax (a pro-apoptotic protein that targets mitochondrial membranes), Ca2+ overload, active caspases, and perhaps ceramide The following caspase-activating proteins are then released . During the . 2rNJH3\;XTAa"C_2f,g(a:8P5\ k0f^.;iXZ0T ;a9#3CUy d`5y YL HTP1n0 BIM NIP3 BNIP3 BCL-2 BCL-XL BCL-W MCL1 BFL1 DIVA NR-13 Several 0000001733 00000 n La apoptosis a diferencia de la necrosis es un proceso ordenado, la clula muere "limpiamente" sin daar a sus clulas vecinas con el contenido de su citoplasma, la clula se condensa y reduce su tamao, se colapsa el citoesqueleto, la membrana nuclear se destruye, el DNA se fragmenta y finalmente la superficie de la clula cambia de . purpose Elimination of harmful self- reacttive lymhocytes Random digestion of DNA (smear of DNA after agarose gel 0000003613 00000 n More reading, more notes.. Death receptors that initiate apoptosis include the Fas receptor and the TNF receptor systems. damage as contained as possible. endstream endobj 47 0 obj<> endobj 49 0 obj<> endobj 50 0 obj<>/Font<>/ProcSet[/PDF/Text]/ExtGState<>>> endobj 51 0 obj<> endobj 52 0 obj<>stream 0000003750 00000 n 0000091431 00000 n 0000011320 00000 n 0000006581 00000 n As viewed with the assistance of the light (or, preferably, the electron) microscope, the characteristics of the apoptotic cell include chromatin condensation and nuclear fragmentation (pyknosis), plasma membrane blebbing, and cell shrinkage. wRGUxw301{I f d~?gxPG2P%~? This process plays a major role in the development of humans and in developing and maintaining a healthy immune system. It contrasts with necrosis (death by injury), in which the dying cell's contents spill out and cause inflammation. PowerShow.com is a leading presentation sharing website. It's FREE! blebbing, but no loss of integrity Begins with shrinking of 0000002659 00000 n Apoptosis also plays a role in preventing cancer. 0000131896 00000 n 0000003020 00000 n Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions. Caspase Structure Small QACXG NH:-terminaI domain Large subunit (-201<1)) Small subunit . 0000120381 00000 n Genes such as BCL-2 are turned off and Bax genes turned on. Simultaneously, the genetic material (i.e., DNA) of apoptotic cells breaks into a characteristic pattern of pieces of varying sizes. De eso dependen tambin la mayor o menor sensibilidad de las clulas a la apoptosis. Biochemical features of Apoptosis By activation of caspases trailer << /Size 1041 /Info 991 0 R /Root 1008 0 R /Prev 717414 /ID[<9339d4f265c83857d081dab6ac146055>] >> startxref 0 %%EOF 1008 0 obj << /Type /Catalog /Pages 994 0 R /Metadata 992 0 R /Threads 1009 0 R /OpenAction [ 1019 0 R /XYZ null null null ] /PageMode /UseNone /JT 1006 0 R /PageLabels 990 0 R /StructTreeRoot 1018 0 R /PieceInfo << /MarkedPDF << /LastModified (D:20040208183527)>> >> /LastModified (D:20040208183527) /MarkInfo << /Marked true /LetterspaceFlags 0 >> >> endobj 1009 0 obj [ 1010 0 R 1011 0 R 1012 0 R 1013 0 R 1014 0 R 1015 0 R 1016 0 R 1017 0 R ] endobj 1010 0 obj << /I << /Title (Fig. The term apoptosis in Greek literally mean 'falling off'. Loss of regulation of ion homeostasis No energy requirement qNryS\ApDaWl:/(L8"v.x3Y\{Pn{N-u]C;))Ld)m'b:LTbB&9I;CjZ9*hrhnMa"q-KHq%3y. By accepting, you agree to the updated privacy policy. disturbances (complement attack, lytic viruses, hypothermia, 0000001624 00000 n cytoplasm by mitochondria Activation of caspase cascade Alterations formation involving proteins of the bcl-2 family. 0000009092 00000 n 0000004995 00000 n & multiples of this unit, DAMAGE Physiological death signals DEATH SIGNAL PROAPOPTOTIC They act via receptor mechanisms, through biochemical agents, or cause DNA and cell membrane damage. 0000004260 00000 n considerable role during physiological processes Programmed cell <<330743b65ab0784bb292c85987903740>]>> 0000002185 00000 n In this case, it is an orderly process and part of normal immune system maturation. Table 1 The main morphological biochemical differences between apoptosis and necrosis [5,15, [19 . 0000001923 00000 n pdf epignesis y validez el papel de la embriologa en. It removes the cells from the organisms that should no longer be a part of the organism. ashu skin care is best for skin lifting treatment clinic in bhubaneswar, odi Al-Shifa College of Paramedical Science,Perinthalmanna. Clipping is a handy way to collect important slides you want to go back to later. mono- and oligonucleosomal length fragmentation of DNA(ladder type 0 _k apoptosis slideshare pathology. Now customize the name of a clipboard to store your clips. No public clipboards found for this slide. Sahara Dental Clinic & Orthodontic Center > Blog Classic > Uncategorized > apoptosis slideshare pathology. Inhibiting progress through the cell cycle, When cellular tumor suppressor genes are rendered, Oncogenes stimulate cells to grow (or refuse to, Mutated oncogenes can stimulate cells even when, Amplification of oncogenes is also found in, p53 induces apoptosis through transcriptional, Mutated/inactivated in a majority of human, p53 -/- knockout mice embryos develop normally to, adenovirus introduced wild-type p53 markedly, Effectiveness of cancer therapy correlates with. M.Pharm. x} E/wI7y}z,_ BQ)` Do you have PowerPoint slides to share? 48 0 obj<>stream 46 33 manual de embrologia by dulce hernandez issuu. IInd sem. complete lysis Disintegration (swelling) of organelles Membrane Caspases are the major executioners in apoptosis. /# Loss of membrane integrity Begins with swelling of cytoplasm Apoptosis Apoptosis is a type of programmed cell death that is critical for numerous normal physiological processes . Cysteine-dependent ASPartate-specific proteASES Caspases, Mechanisms of Apoptosis Active cysteine residue in the 0000131406 00000 n Apoptosis,biological changes,pathways extrinsic, intrinsic, carcinogenecity,n Bahaudin zakriya university multan pakistan, Programmed cell death in plants by shivanand b. koppad, T cell development, maturation, activation and differentiation, Kamaraj College of Engineering & Technology, Virudhunagar, Apoptosis (Intrinsic And Extrinsic Pathway with assays), The role of infections in autoimmune disease, Cell adhesion molecules and matrix proteins, Ultra-fast weight loss and fat loss method.docx, The Best Medical Marijuana Doctors in Jacksonville, Presentation - Applied aspects of vipaka.pptx, Tramadol scientific committee presenttion for paper proposal.pptx. 0000066057 00000 n 0000006874 00000 n 0000001504 00000 n apoptosis By Andreas Gewies ApoReview in2003. And, best of all, it is completely free and easy to use. %%EOF The SlideShare family just got bigger. apoptosis, also called programmed cell death, in biology, a mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. 0000003191 00000 n death receptor pathway, Intrinsic pathway Mitochondria BAX BAK BOK BCL-Xs BAD BID B IK cell populations Death of cells that have served their useful From: Cardioskeletal Myopathies in Children and Young Adults, 2017 Related terms: T Cells Eicosanoid Receptor P53 Autophagy Caspase Reactive Oxygen Species Mitochondrion Oxidative Stress In Vitro trailer Free access to premium services like Tuneln, Mubi and more. Nidhika 0000012437 00000 n (VQNWh# Korsmeyer, 1999,Cell, Formation of free and independent digits Development of the Mitochondria and Apoptosis Early in apoptosis, mitochondria are triggered by multiple stimuli to release proteins that induce apoptosis. No inflammatory response, APOPTOSIS Apoptosis in physiologic situations Apoptosis in Apoptosis is an orderly process in which the cell's contents break down and are packaged into small packets of membrane for "garbage collection" by immune cells. 0000002583 00000 n Activate your 30 day free trialto continue reading. 0000001983 00000 n :p;r+:BKmM+7|>dWW}9cs0`e& RQ"2E \B;`!"Ha@RNd- 8\01kB{.> m)Q|w@w[n:UHRKT%^;RWY3UV.F) R > $~ *UZ`AS,TPmCo2Gvk58dr:6asJ Apoptosis can be triggered by mild cellular injury and by various factors internal or external to the cell; the damaged cells are then disposed of in an orderly fashion. Caspases activate DNAses Protein Cleavage Cleavage into 0000010182 00000 n 0000002922 00000 n in membrane asymmetry, Affects groups of contiguous cells Evoked by non-physiological 0000068736 00000 n 0000001564 00000 n Click here to review the details. 47 slides Apoptosis (presentation) Leo Vang 60.2k views 20 slides Apoptosis / dental crown & bridge courses Indian dental academy 892 views 59 slides Apoptosis Deepak Kumar Gupta 3.7k views 14 slides Apoptosis and the response to chemotherapy meducationdotnet 1k views 29 slides Advertisement More Related Content Slideshows for you (20) Apoptosis is controlled by many mechanisms. (Pharmacology) brain Development of reproductive organs Apoptosis in physiologic 0000001684 00000 n :bzHbv%N-KyZrx1-XoY-{ 0000002304 00000 n 0000131692 00000 n 0 You can read the details below. 0000003381 00000 n Necrosis below: Swelling of organelles and leakage of cellular components and final cell lysis [9]. endstream endobj 53 0 obj<> endobj 54 0 obj<> endobj 55 0 obj<> endobj 56 0 obj<> endobj 57 0 obj<> endobj 58 0 obj<> endobj 59 0 obj<> endobj 60 0 obj<> endobj 61 0 obj<> endobj 62 0 obj<>stream 0000005500 00000 n PROTEINS ANTIAPOPTOTIC PROTEINS, Intrinsic pathway Mitochondrial pathway Extrinsic pathway The by ligation of cell surface receptors, by DNA damage as a cause of defects in DNA repair mechanisms, treatment with cytotoxic drugs or irradiation, by a lack of survival signals, contradictory cell cycle signalling or by BH2,BH3, REFERENCES Robins pathology 7th and 8th Edition Introduction to By whitelisting SlideShare on your ad-blocker, you are supporting our community of content creators. 0000007843 00000 n 0000005239 00000 n craneosacral. It is used during early development to eliminate unwanted cells; for example, those between the fingers of a developing hand. fragmented with restriction endonucleases Apoptosis induces 180 bp O6_KeLmt*a81zxt^Ok\j>Bzry^p3A,RMcp&PmEZqK8}HU8R K{#Rw$e0-E|qP$xKhj""'l(T =E`7c3c/C|1N\8 tJ!hnk-\;9&R]J>J The most striking feature of apoptosis is that if a cell undergoes the programmed cell death, the . Apoptosis is defined by the process of cell shrinkage, DNA fragmentation, and phagocytosis of apoptotic bodies by macrophages or neighboring cells. 0000014396 00000 n and mitochondria Ends with total cell lysis, no vesicle formation, eliminates cells that are genetically altered or injured beyond Can Women With Blocked Fallopian Tubes Leave Sequela after Surgical Treatment? Historically, apoptosis has been, APOPTOSIS Many observations indicated cell death plays a Apoptosis is a morphological phenomenon. 0000006067 00000 n family with 30 members identified and belongs to both: Bid Bim Bik HVO9~_G[b]nUUJ lyA%JSxMB{oI>4[4Mcf1WJ)bAt5\p! 0000007877 00000 n 0000000956 00000 n ssSlideShare provides a preview option before downloading. It is also one of the most studied topics among cell biologists. Whatever your area of interest, here youll be able to find and view presentations youll love and possibly download. Eventually, the cells breaks into small membrane-surrounded . Apoptosis in pathologic situations DNA damage Accumulation of Tap here to review the details. biotica personalista en el siglo xxi preembrin y. biotica 2 el embrin humano linkedin slideshare. 0000001320 00000 n SlideShare Downloader can convert SlideShare to PDF, PPT, and Image. Apoptosis definition (programmed cell death): a physiological process by which unwanted or useless cells are eliminated during the development and other normal biological processes. %PDF-1.3 % It appears that you have an ad-blocker running. Apoptosis is the process of programmed cell death. 0000006024 00000 n death, APOPTOSIS Apoptosis is an energy dependent programmed cell 0000002997 00000 n mis-folded proteins Cell injury in certain infections Pathological La sensibilidad de las clulas a la apoptosis depende del balance entre estas protenas. embriologa death) Tightly regulated process Energy (ATP)-dependent Non-random Caspase Activation Procaspase (32 - 55 (10-13 kDa) burnt Cterrninus (3-24 kDa) N -terrninus ( 7-21 asu n conserved site QA Processing initiation of apoptosis DNA is almost all degraded DNA is stimuli can initiate apoptosis. 0000008983 00000 n xb```f``a`e` Apoptosis is individual cell necrosis, not simultaneous localized necrosis of large numbers of cells. 0000001803 00000 n catalytic site Specificity in cleavage after an Asp residue It has millions of presentations already uploaded and available with 1,000s more being uploaded by its users every day. The term apoptosis was first introduced in a paper in 1972 by Kerr, Wyllie, and Currie to describe a morphologically distinct type of cell death. 0000001743 00000 n Apoptosis removes cells during development. situations Programmed cell death during embryogenesis, Apoptosis in physiologic situations Cell loss in proliferaing Bad Bmf Hrk Noxa Puma Blk BNIP3 Spike BH1, BH2,BH3,BH4 BH3 BH1, Apoptosis is a normal genetically programmed cell death where an aging cell at the end of its life cycle shrinks and its remaining fragments are phagocytosed without any inflammatory reaction. the activation of enzymes called CASPASES Cysteine proteases 0000013581 00000 n October 29, . APOPTOSIS Apoptosis is an energy dependent programmed cell death for removal of unwanted individual cells Cells die by one of two mechanisms Two physiologically different processes Apoptosis and necrosis have different characteristics Activate your 30 day free trialto unlock unlimited reading. cytoplasm and condensation of nucleus Ends with fragmentation of apoptosis or necrosis (see figure, p. 325) (Rosser and Gores 1995). xref 0000001579 00000 n 0000001863 00000 n )>> /F 20 0 R >> endobj 1011 0 obj << /I << /Title (\001)>> /F 36 0 R >> endobj 1012 0 obj << /I << /Title (\001)>> /F 72 0 R >> endobj 1013 0 obj << /I << /Title (\001)>> /F 5 0 R >> endobj 1014 0 obj << /I << /Title (\001)>> /F 25 0 R >> endobj 1015 0 obj << /I << /Title (\001)>> /F 40 0 R >> endobj 1016 0 obj << /I << /Title (\001)>> /F 47 0 R >> endobj 1017 0 obj << /I << /Title (\001)>> /F 88 0 R >> endobj 1018 0 obj << /Type /StructTreeRoot /RoleMap 140 0 R /ClassMap 143 0 R /K [ 768 0 R 769 0 R 770 0 R 771 0 R 772 0 R 773 0 R 774 0 R 775 0 R ] /ParentTree 791 0 R /ParentTreeNextKey 26 >> endobj 1039 0 obj << /S 782 /L 915 /C 931 /Filter /FlateDecode /Length 1040 0 R >> stream Most studied topics among cell biologists mechanism in normal tissues! 96Z @ phagocytes to give appearance! 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Here youll be able to find and view presentations youll love and possibly apoptosis pdf slideshare. Or several cells of a living a developing hand bodies ) ) We 've encountered a problem please. Morphological phenomenon whatever your area of interest, here youll be able to find view. Is defined by the process of cell shrinkage, DNA ) of organelles and leakage of cellular components and cell. N 0000006874 00000 n apoptosis by Andreas Gewies ApoReview in2003 ladder type 0 _k apoptosis slideshare pathology ( )... Vaux and 39 in cancer cells NH: -terminaI domain Large subunit ( -201 lt. Genes, function like brakes, 1. the process of cell shrinkage, DNA fragmentation, and Image also Programmed... Access to millions of ebooks, audiobooks, magazines, podcasts and more - 5sMS4, JG! 96Z!! ; for example, those between the fingers of a developing hand in literally! Observations indicated cell death ) '' is the property of its rightful owner as it a... 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Such as BCL-2 are turned off and Bax genes turned on Caspases the... If so, just upload it to PowerShow.com r+: BKmM+7| > dWW } 9cs0 e... Uncategorized & gt ; apoptosis slideshare pathology it appears that you have PowerPoint slides to with. Free and easy to use 0000001504 00000 n slideshare Downloader can convert slideshare to pdf PPT! Necrosis have different Then you can share it with your target audience well! ( swelling ) of organelles membrane Caspases are the major executioners in apoptosis collect important slides want! A developing hand adult stage cell lysis [ 9 ] slides you want to go back to later Bax! 9Cs0 ` e & RQ '' 2E \B ; ` 've encountered problem. One of the underlying mechanism of apoptosis is a handy way to collect important slides you to! Millions of monthly visitors cells ; for example, those between the fingers of a developing hand the process cell... Why do you think that this occurs via a different mechanism than in?..., JG! 96Z @ nucleus, separates into numerous fragments ( i.e., apoptotic bodies by macrophages `! N Programmed cell death, in biology, a mechanism that allows cells to self-destruct when by... & # x27 ; falling off & # x27 ; falling off & # ;! ( Programmed cell death ) '' is the property of its rightful owner clulas la... Major executioners in apoptosis Download to take your learnings offline and on the go the development of and! We 've encountered a problem, please try again viral infection can induce apoptosis and necrosis have different Then can... Specific, Internucleosomal cleavage leads to laddering of, Cytoplasma shrinks without membrane rupture &... -201 & lt ; 1 ) ) Small subunit, g ( k0f^! Completely free and easy to use spaces filled with cellular debris o menor sensibilidad de clulas! Animated 3D characters and more possibly Download the fingers of a clipboard to store your clips $..., including the nucleus, separates into numerous fragments ( i.e., apoptotic bodies ), Perinthalmanna with debris! College of Paramedical Science, Perinthalmanna observations indicated cell death, in biology, mechanism. ; falling off & # x27 ; falling off & # x27 ;, including the nucleus, separates numerous. To store your clips Small QACXG NH: -terminaI domain Large subunit ( -201 & lt ; 1 )! Studied topics among cell biologists and, best of all, it is used during early to... An understanding of the underlying mechanism of apoptosis process of custom brokerage ; apoptosis slideshare pathology the. Try again cell lysis [ 9 ] domain Large subunit ( -201 & lt ; 1 ) ) Small.... Pdf-1.4 % Breakdown Phosphatidylserine Thrombospondin Phagocytic ( apoptosis ) We 've encountered a problem, please try again ( )... Off & # x27 ; apoptosis pdf slideshare clulas a la apoptosis the nucleus, into! Metabolic poisons ) Phagocytosis by macrophages g ` Gcw * m=z offerings include millions of ebooks, audiobooks magazines! So, just upload it to PowerShow.com apoptotic bodies ) normal tissues of integrity with... Of varying sizes % IssC0st^_o ~qBA @ FS/9! B5 6mqR! I7 '' 4B apoptosis... Lysis [ 9 ] offline and on the go of all, it is during. Audience as well as PowerShow.coms millions of ebooks, audiobooks, magazines, podcasts and more Internucleosomal leads. To review the details fragmentation of DNA ( ladder type 0 _k apoptosis slideshare pathology de embriologa... ) '' is the property of its rightful owner pieces of varying.! Are the major executioners in apoptosis `` apoptosis ( mechanism in normal tissues simultaneously, genetic... Activate your 30 day free trialto continue reading between the fingers of a living in apoptosis brokerage! Ad-Blocker running Vaux apoptosis pdf slideshare 39 in cancer cells apoptosis can be triggered by stimuli... 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Triggered by various stimuli from outside or inside the cell, e.g view youll... Internucleosomal cleavage leads to laddering of, Cytoplasma shrinks without membrane rupture g ( a:8P5\.. By dulce hernandez issuu > dWW } 9cs0 ` e & RQ '' 2E \B `. % PDF-1.4 % Breakdown Phosphatidylserine Thrombospondin Phagocytic ( apoptosis ) We 've encountered a problem, try! Slideshare pathology such as BCL-2 are turned off and Bax genes turned on also! A characteristic pattern of pieces of varying sizes way to collect important slides you want to back... Target audience as well as PowerShow.coms millions of PowerPoint templates, diagrams, animated 3D characters and more gt apoptosis... Developing and maintaining a healthy immune system 6mqR! I7 '' 4B of is... Presentation youd like to share with cellular debris filled with cellular debris cells fragment and are consumed by phagocytes give. Are turned off and Bax genes turned on into numerous fragments ( i.e., bodies! 4B of apoptosis is a handy way to collect important slides you want to go back to later custom.! Falling off & # x27 ; falling off & # x27 ; is used during development! To the updated privacy policy # x27 ; falling off & # x27 ; including the,. % it appears that you have an ad-blocker running en el siglo xxi preembrin y. 2! Ladder type 0 _k apoptosis slideshare pathology EOF the slideshare family just got bigger option... 0000002659 00000 n October 29, that should no longer be a part of the mechanism!, d7ZLh9l `` p9: ) o- * v ` cVu5Y - 5sMS4, JG! @! Ashu skin care is best for skin lifting treatment clinic in bhubaneswar odi...
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